Details
The Role of Water in ATP Hydrolysis Energy Transduction by Protein Machinery
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117,69 € |
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| Verlag: | Springer |
| Format: | |
| Veröffentl.: | 07.05.2018 |
| ISBN/EAN: | 9789811084591 |
| Sprache: | englisch |
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Beschreibungen
This book introduces recent progress in biological energetics from ATP hydrolysis to molecular machineries. The role of water is now recognized to be essential in biological molecular energetics. Although energetics is a rather distant field to many biologists, any working models for protein machineries such as protein motors, transporters, and other enzymes must be consistent with their energetics. Therefore, the book is intended to help scientists build systematic models of biomolecular functions based on three categories: (1) ATP hydrolysis reactions including ionic hydration and protonation–deprotonation of biomolecules, (2) protein–ligand/protein–protein interactions including hydration–dehydration processes, and (3) functioning mechanisms of protein machineries based on water functions. <div><br></div>
Part I: Basis of ATP Hydrolysis Reaction<p>1. Free Energy Analyses for the ATP Hydrolysis in Aqueous Solution by Large-Scale QM/MM Simulations Combined with a Theory of Solutions</p>
<p>Hideaki Takahashi</p>
2. Role of Metal Ion Binding and Protonation in ATP Hydrolysis Energetics<p></p>
<p>Shun-ichi Kidokoro</p>
<p>3. Spatial Distribution of Ionic Hydration Energy and Hyper-mobile Water</p>
<p>George Mogami, Makoto Suzuki and Nobuyuki Matubayasi</p>
<p>4. Theoretical studies of strong attractive interaction between macro-anions mediated by multivalent metal cations and related association behavior: Effective interaction between ATP binding proteins can be regulated by hydrolysis.</p>
<p>Ryo Akiyama </p>
<p>5. Statistical mechanical integral equation approach to reveal the solvation effect on hydrolysis free energy of ATP and its analogue</p>
Norio Yoshida and Fumio Hirata<p></p>
<p>6. A Solvent Model of Nucleotide–protein interaction - Partition coefficients of phosphates in solvent-water mixtures- </p>
<p>Hideyuki Komatsu</p>
<p> </p>
<p>Part II: Basis of Protein-Ligand and Protein-Protein Interactions</p>
<p>7. Energetics of myosin-ATP hydrolysis by calorimetry</p>
<p> Takao Kodama</p>
<p>8. Orchestrated electrostatic interactions among myosin, actin, ATP, and water</p>
<p> Mitsunori Takano</p>
<p>9. Protonation/deprotonation of proteins by neutron diffraction structure analysis</p>
<p> Ichiro Tanaka, Katsuhiro Kusaka, Nobuo Niimura</p>
<p>10. All-atom analysis of free energy of protein solvation through molecular simulation and solution theory</p>
<p> Nobuyuki Matubayasi</p>
<p>11. Uni-directional propagation of structural changes in actin filaments</p>
<p> Taro Q. P. Uyeda, Kien Xuan Ngo, Noriyuki Kodera, Kiyotaka Tokuraku</p>
<p>12. Functional mechanisms of ABC transporters as revealed by molecular simulations</p>
<p>Tadaomi Furuta, Minoru Sakurai</p>
<p>13. Statistical thermodynamics on the binding of biomolecules</p>
<p>Tomohiko Hayashi</p>
<p> </p>
<p>Part III: Functioning Mechanisms of Protein Machinery</p>
<p>14. Ratchet model of motor proteins and its energetics</p>
<p>Yohei Nakayama and Eiro Muneyuki</p>
<p>15. Single Molecule Analysis of Actomyosin in the Presence of Osmolyte</p>
<p>Mitsuhiro Iwaki, Kohji Ito and Keisuke Fujita</p>
<p>16. Novel intermolecular surface force unveils the driving force of actomyosin system</p>
<p>Makoto Suzuki, George Mogami, Takahiro Watanabe, and Nobuyuki Matubayasi</p>
<p>17. Extremophilic enzymes related to energy conversion</p>
Satoshi Wakai and Yoshihiro Sambongi<p></p>
<p>18. Functioning mechanism of ATP-driven proteins inferred on the basis of water-entropy effect </p>
<p>Masahiro Kinoshita</p>
19. Controlling the motility of ATP-driven molecular motors using high hydrostatic pressure<p></p>
<p>Masayoshi Nishiyama</p>
<p>20. Modulation of the sliding movement of myosin-driven actin filaments associated with their distortion: The effect of ATP, ADP, and inorganic phosphate</p>
<p>Kuniyuki Hatori and Satoru Kikuchi</p>
<p>Hideaki Takahashi</p>
2. Role of Metal Ion Binding and Protonation in ATP Hydrolysis Energetics<p></p>
<p>Shun-ichi Kidokoro</p>
<p>3. Spatial Distribution of Ionic Hydration Energy and Hyper-mobile Water</p>
<p>George Mogami, Makoto Suzuki and Nobuyuki Matubayasi</p>
<p>4. Theoretical studies of strong attractive interaction between macro-anions mediated by multivalent metal cations and related association behavior: Effective interaction between ATP binding proteins can be regulated by hydrolysis.</p>
<p>Ryo Akiyama </p>
<p>5. Statistical mechanical integral equation approach to reveal the solvation effect on hydrolysis free energy of ATP and its analogue</p>
Norio Yoshida and Fumio Hirata<p></p>
<p>6. A Solvent Model of Nucleotide–protein interaction - Partition coefficients of phosphates in solvent-water mixtures- </p>
<p>Hideyuki Komatsu</p>
<p> </p>
<p>Part II: Basis of Protein-Ligand and Protein-Protein Interactions</p>
<p>7. Energetics of myosin-ATP hydrolysis by calorimetry</p>
<p> Takao Kodama</p>
<p>8. Orchestrated electrostatic interactions among myosin, actin, ATP, and water</p>
<p> Mitsunori Takano</p>
<p>9. Protonation/deprotonation of proteins by neutron diffraction structure analysis</p>
<p> Ichiro Tanaka, Katsuhiro Kusaka, Nobuo Niimura</p>
<p>10. All-atom analysis of free energy of protein solvation through molecular simulation and solution theory</p>
<p> Nobuyuki Matubayasi</p>
<p>11. Uni-directional propagation of structural changes in actin filaments</p>
<p> Taro Q. P. Uyeda, Kien Xuan Ngo, Noriyuki Kodera, Kiyotaka Tokuraku</p>
<p>12. Functional mechanisms of ABC transporters as revealed by molecular simulations</p>
<p>Tadaomi Furuta, Minoru Sakurai</p>
<p>13. Statistical thermodynamics on the binding of biomolecules</p>
<p>Tomohiko Hayashi</p>
<p> </p>
<p>Part III: Functioning Mechanisms of Protein Machinery</p>
<p>14. Ratchet model of motor proteins and its energetics</p>
<p>Yohei Nakayama and Eiro Muneyuki</p>
<p>15. Single Molecule Analysis of Actomyosin in the Presence of Osmolyte</p>
<p>Mitsuhiro Iwaki, Kohji Ito and Keisuke Fujita</p>
<p>16. Novel intermolecular surface force unveils the driving force of actomyosin system</p>
<p>Makoto Suzuki, George Mogami, Takahiro Watanabe, and Nobuyuki Matubayasi</p>
<p>17. Extremophilic enzymes related to energy conversion</p>
Satoshi Wakai and Yoshihiro Sambongi<p></p>
<p>18. Functioning mechanism of ATP-driven proteins inferred on the basis of water-entropy effect </p>
<p>Masahiro Kinoshita</p>
19. Controlling the motility of ATP-driven molecular motors using high hydrostatic pressure<p></p>
<p>Masayoshi Nishiyama</p>
<p>20. Modulation of the sliding movement of myosin-driven actin filaments associated with their distortion: The effect of ATP, ADP, and inorganic phosphate</p>
<p>Kuniyuki Hatori and Satoru Kikuchi</p>
Makoto Suzuki graduated from Yamagata University in 1974 and received his Doctor of Engineering degree from Tohoku University in 1981. Following his studies, he worked at the Mechanical Engineering Laboratory (MEL/AIST) for eleven years, and at the National Institute for Advanced Interdisciplinary Research (NAIR/AIST) for five years. <div>He moved from NAIR to Tohoku University as a professor in 1996. Using his improved-high-precision system of dielectric spectroscopy, he discovered hyper-mobile water (HMW) in the hydration layer of actin filaments, one of the contractile muscle proteins, in 2003. He organized "Water Plays the Main Role in ATP Energy Transfer" (2008-2012) as an Innovative Scientific Research Area, an interdisciplinary project focused on the energetics of protein machineries.</div><div><br></div>
This book introduces recent progress in biological energetics from ATP hydrolysis to molecular machineries. The role of water is now recognized to be essential in biological molecular energetics. Although energetics is a rather distant field to many biologists, any working models for protein machineries such as protein motors, transporters, and other enzymes must be consistent with their energetics. Therefore, the book is intended to help scientists build systematic models of biomolecular functions based on three categories: (1) ATP hydrolysis reactions including ionic hydration and protonation–deprotonation of biomolecules, (2) protein–ligand/protein–protein interactions including hydration–dehydration processes, and (3) functioning mechanisms of protein machineries based on water functions. <div><br></div>
<p>Provides approaches to the essence of life functions</p><p>Links biology and chemical physics</p><p>Sets forth revolutionary concepts for biological molecular functions</p>
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